Investigation of Cardiomyocyte Proliferation on Fractionated Cardiac Extracellular Matrix Derived from Perfusion-Decellularized Ventricular Tissue

نویسندگان

  • Kyle Edmunds
  • Corin Williams
  • Ngonidzashe Madungwe
چکیده

[1] Grady, KL, “Management of heart failure in older adults”, Journal of Cardiovascular Nursing, 2006 Sep-Oct, S10-4 [2] French, KM et al, “A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro”, Acta Biomaterialia, 2012 Dec, 4357-64 [3] Singelyn, JM et al, “Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering”, Biomaterials, 2009 Oct, 5409-16 [4] Agrawal, V et al, “An isolated cryptic peptide influences osteogenesis and bone remodeling in an adult mammalian model of digit amputation”, Tissue Engineering Part A, 2011 Oct, 2435-2443 [5] Ott, HC et al, “Perfusion-decellularized matrix: using nature’s platform to engineer a bioartificial heart”, Nature Materials, 2008 Feb, 213-21 Investigation of Cardiomyocyte Proliferation on Fractionated Cardiac Extracellular Matrix Derived from Perfusion-Decellularized Ventricular Tissue

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Reinforcement of a decellularized extracellular matrix-derived hydrogel using nanofibers for cardiac tissue engineering

The role of heart disease in increasing worldwide death and the limited availability of organs for transplantation have encouraged multiple strategies to fabricate functional and implantable constructs. One of these strategies is to develop a biologically similar heart tissue scaffold, in which two types of fiber and hydrogel are commonly used. Toward this goal, taking advantage of both hydroge...

متن کامل

Reinforcement of a decellularized extracellular matrix-derived hydrogel using nanofibers for cardiac tissue engineering

The role of heart disease in increasing worldwide death and the limited availability of organs for transplantation have encouraged multiple strategies to fabricate functional and implantable constructs. One of these strategies is to develop a biologically similar heart tissue scaffold, in which two types of fiber and hydrogel are commonly used. Toward this goal, taking advantage of both hydroge...

متن کامل

Repopulation of decellularized mouse heart with human induced pluripotent stem cell-derived cardiovascular progenitor cells.

Heart disease is the leading cause of death in the world. Heart tissue engineering holds a great promise for future heart disease therapy by building personalized heart tissues. Here we create heart constructs by repopulating decellularized mouse hearts with human induced pluripotent stem cell-derived multipotential cardiovascular progenitor cells. We show that the seeded multipotential cardiov...

متن کامل

Mesenchymal stem cells can survive on the extracellular matrix-derived decellularized bovine articular cartilage scaffold

Objective (s): The scarcity of articular cartilage defect to repair due to absence of blood vessels and tissue engineering is one of the promising approaches for cartilage regeneration. The objective of this study was to prepare an extracellular matrix derived decellularized bovine articular cartilage scaffold and investigate its interactions with seeded rat bone marrow mesenchymal stem cells (...

متن کامل

Cardiogel as an Instructive Microenvironment for in vitro Differentiation of Bone Marrow- Derived Mesenchymal Stem Cells into Cardiomyocytes

Background: Stem cell therapy has been developed as an effective treatment method for the heart failure. Also, extracellular matrix has shown the positive effects in stem cell differentiation and myocardial tissue organization. Cardiogel is a native cardiac extracellular matrix (ECM) derived from cardiac fibroblasts. In the present study the role of cardiogel is examin...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013